Jonathan DeWeese is a board-certified psychiatric mental health nurse practitioner (PMHNP), as well as a board-certified adult-gerontology primary care nurse practitioner. He currently works in private practice in Central Square, Cambridge, and is a current post-graduate fellow at the Psychotherapy Institute of Back Bay where he sees individual and couples psychotherapy patients in Copley Square, Boston. Jonathan is particularly interested in psychodynamic psychotherapy, relationship issues, masculinity and men’s issues, spiritual/existential issues, aging, death and  dying, LGBTQ issues, and psychedelic integration and harm reduction. 

Prior to moving into private practice full-time, he worked for two years in geriatric psychiatry at Cambridge Health Alliance, a Harvard Medical School teaching hospital. Jonathan’s clinical and nursing foundation came from Massachusetts General Hospital, another Harvard Medical School teaching hospital, where he trained and worked for ten years.

Clinically, Jonathan has experience in inpatient, outpatient, emergency, correctional, and hospice settings. He works with a number of mental health concerns including mood and anxiety disorders, ADHD, and substance use disorders. He is also passionate about ketamine-assisted psychotherapy (KAP) as both a prescriber and a KAP therapist, and he partners with KAP therapists to prescribe ketamine to their clients for this purpose. With advanced training in psychopharmacology, psychotherapy, and psychedelic-assisted psychotherapy, Jonathan finds supporting his patients’ flourishing and accompanying them across the range of their human experience deeply fulfilling work.


  • California Institute of Integral Studies: Certificate in Psychedelic-Assisted Therapies and Research (2022)
  • The University of New Hampshire: Post-Masters Psychiatric Mental Health Nurse Practitioner Graduate Certificate (2021)
  • The MGH Institute of Health Professions: Bachelors and Masters of Science in Nursing (2015)
  • The University of Chicago: BA in South Asian Languages and Civilizations (2010)
  • Deep Springs College (2009)


  • Psychotherapy Institute of Back Bay Post-Graduate Fellowship in Adult and Couples Psychodynamic Psychotherapy (2022-24)
  • Psychodynamic Couple & Family Institute of New England Post-Graduate Couple Therapy Program (2022-23)
  • Massachusetts Institute for Psychoanalysis Post-Graduate Fellowship Program (2021-22)
  • Swartz Fellowship in Spiritual Care at Massachusetts General Hospital entailing three units of Clinical Pastoral Education, or CPE (2015-16)


  • Intensive training in guiding individual altered-state experiences in the Ralph Metzner lineage (2024-2025)
  • Steward for the Hero’s Journey Foundation Men’s Summer Intensive Program (2022, 2023, and 2024) 
  • Northeastern Society for Group Psychotherapy Observation Group training (2023) 
  • Accelerated Experiential Dynamic Psychotherapy (AEDP) Immersion Course (2022)
  • MAPS Therapist Training Program for MDMA-assisted psychotherapy (2021)
  • Ketamine-assisted psychotherapy modules one through six and the medical module from Polaris Insight Center (2020-23)


  • DeWeese, JP. Spiritual Care for Substance Use Disorders. Presentation to MGH CPE Spiritual Care Residents and Interns. Twice annually since 2019.
  • DeWeese, JP. Psychedelics and Spiritual Care. Presentation to MGH Spiritual Care Department.  February, 2022 and July, 2023.
  • DeWeese JP, Krenz JR, Wakeman SE, Peckham AM. Rapid buprenorphine microdosing for opioid use disorder in a hospitalized patient receiving very high doses of full agonist opioids for acute pain management: Titration, implementation barriers, and strategies. Subst Abus. 2021 May 4:1-6. doi: 10.1080/08897077.2021.1915914
  • DeWeese, JP. Microdosing and Extended-Release Buprenorphine. Presenter at the MGH Psychiatry Academy’s Substance Use Disorders: A Comprehensive Review and Update 2021 Conference. February 16, 2021


  • Professional Advisory Committee for the Massachusetts General Hospital’s Clinical Pastoral Education Program, 2019 to present 
  • Trustees of Deep Springs College, Board Member and Secretary, 2021 to present 


  • Massachusetts, Wyoming, Idaho